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Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

INTRODUCTION: Tumor lymphocyte infiltration is associated with clinical response to chemotherapy in estrogen receptor (ER) negative breast cancer. To identify variants in immunosuppressive pathway genes associated with prognosis after adjuvant chemotherapy for ER-negative patients, we studied stage...

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Autores principales: Lei, Jieping, Rudolph, Anja, Moysich, Kirsten B, Rafiq, Sajjad, Behrens, Sabine, Goode, Ellen L, Pharoah, Paul PD, Seibold, Petra, Fasching, Peter A, Andrulis, Irene L, Kristensen, Vessela N, Couch, Fergus J, Hamann, Ute, Hooning, Maartje J, Nevanlinna, Heli, Eilber, Ursula, Bolla, Manjeet K, Dennis, Joe, Wang, Qin, Lindblom, Annika, Mannermaa, Arto, Lambrechts, Diether, García-Closas, Montserrat, Hall, Per, Chenevix-Trench, Georgia, Shah, Mitul, Luben, Robert, Haeberle, Lothar, Ekici, Arif B, Beckmann, Matthias W, Knight, Julia A, Glendon, Gord, Tchatchou, Sandrine, Alnæs, Grethe I Grenaker, Borresen-Dale, Anne-Lise, Nord, Silje, Olson, Janet E, Hallberg, Emily, Vachon, Celine, Torres, Diana, Ulmer, Hans-Ulrich, Rüdiger, Thomas, Jager, Agnes, van Deurzen, Carolien HM, Tilanus-Linthorst, Madeleine MA, Muranen, Taru A, Aittomäki, Kristiina, Blomqvist, Carl, Margolin, Sara, Kosma, Veli-Matti, Hartikainen, Jaana M, Kataja, Vesa, Hatse, Sigrid, Wildiers, Hans, Smeets, Ann, Figueroa, Jonine, Chanock, Stephen J, Lissowska, Jolanta, Li, Jingmei, Humphreys, Keith, Phillips, Kelly-Anne, Linn, Sabine, Cornelissen, Sten, van den Broek, Sandra Alexandra J, Kang, Daehee, Choi, Ji-Yeob, Park, Sue K, Yoo, Keun-Young, Hsiung, Chia-Ni, Wu, Pei-Ei, Hou, Ming-Feng, Shen, Chen-Yang, Teo, Soo Hwang, Taib, Nur Aishah Mohd, Yip, Cheng Har, Ho, Gwo Fuang, Matsuo, Keitaro, Ito, Hidemi, Iwata, Hiroji, Tajima, Kazuo, Dunning, Alison M, Benitez, Javier, Czene, Kamila, Sucheston, Lara E, Maishman, Tom, Tapper, William J, Eccles, Diana, Easton, Douglas F, Schmidt, Marjanka K, Chang-Claude, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374346/
https://www.ncbi.nlm.nih.gov/pubmed/25849327
http://dx.doi.org/10.1186/s13058-015-0522-2