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Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics: study protocol for a randomized controlled trial

BACKGROUND: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries. Inappropriate empiric antimicrobial treatment is associated with increased morta...

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Detalles Bibliográficos
Autores principales: Rosso-Fernández, Clara, Garnacho-Montero, José, Antonelli, Massimo, Dimopoulos, George, Cisneros, José Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374401/
https://www.ncbi.nlm.nih.gov/pubmed/25872790
http://dx.doi.org/10.1186/s13063-015-0614-4