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Upregulation of the zebrafish Nogo-A homologue, Rtn4b, in retinal ganglion cells is functionally involved in axon regeneration

BACKGROUND: In contrast to mammals, zebrafish successfully regenerate retinal ganglion cell (RGC) axons after optic nerve section (ONS). This difference is explained on the one hand by neurite growth inhibitors in mammals (including Nogo-A), as opposed to growth-promoting glial cells in the fish vis...

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Detalles Bibliográficos
Autores principales: Welte, Cornelia, Engel, Sarah, Stuermer, Claudia A O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374419/
https://www.ncbi.nlm.nih.gov/pubmed/25888884
http://dx.doi.org/10.1186/s13064-015-0034-x