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SULF2 overexpression positively regulates tumorigenicity of human prostate cancer cells
BACKGROUND: SULF2 is a 6-O-endosulfatase which removes 6-O sulfate residues from N-glucosamine present on heparan sulfate (HS). The sulfation pattern of HS influences signaling events mediated by heparan sulfate proteoglycans (HSPGs) located on cell surface, which are critical for the interactions w...
Autores principales: | Vicente, Carolina M, Lima, Marcelo A, Nader, Helena B, Toma, Leny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374423/ https://www.ncbi.nlm.nih.gov/pubmed/25887999 http://dx.doi.org/10.1186/s13046-015-0141-x |
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