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Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico

We describe the first application of high-resolution 3D micro-computed tomography, together with 3D landmarks and geometric morphometrics, to map QTL responsible for variation in skull shape and size using a backcross between C57BL/6J and A/J inbred strains. Using 433 animals, 53 3D landmarks, and 8...

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Detalles Bibliográficos
Autores principales: Maga, A. Murat, Navarro, Nicolas, Cunningham, Michael L., Cox, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374467/
https://www.ncbi.nlm.nih.gov/pubmed/25859222
http://dx.doi.org/10.3389/fphys.2015.00092