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Photodynamic diagnosis of pleural malignant lesions with a combination of 5-aminolevulinic acid and intrinsic fluorescence observation systems

BACKGROUND: We have developed a new diagnostic method using the photosensitizer 5-aminolevulinic acid (5ALA) for diagnosing intrathoracic malignant lesions. When ingested exogenously, 5ALA is metabolized to a heme precursor, protoporphyrin IX, which stays in malignant cells and emits red to pink lum...

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Detalles Bibliográficos
Autores principales: Kitada, Masahiro, Ohsaki, Yoshinobu, Matsuda, Yoshinari, Hayashi, Satoshi, Ishibashi, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374504/
https://www.ncbi.nlm.nih.gov/pubmed/25886532
http://dx.doi.org/10.1186/s12885-015-1194-0