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Synaptotagmin 1 directs repetitive release by coupling vesicle exocytosis to the Rab3 cycle
In response to Ca(2+) influx, a synapse needs to release neurotransmitters quickly while immediately preparing for repeat firing. How this harmonization is achieved is not known. In this study, we found that the Ca(2+) sensor synaptotagmin 1 orchestrates the membrane association/disassociation cycle...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374511/ https://www.ncbi.nlm.nih.gov/pubmed/25710274 http://dx.doi.org/10.7554/eLife.05118 |