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Synaptotagmin 1 directs repetitive release by coupling vesicle exocytosis to the Rab3 cycle

In response to Ca(2+) influx, a synapse needs to release neurotransmitters quickly while immediately preparing for repeat firing. How this harmonization is achieved is not known. In this study, we found that the Ca(2+) sensor synaptotagmin 1 orchestrates the membrane association/disassociation cycle...

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Detalles Bibliográficos
Autores principales: Cheng, Yunsheng, Wang, Jiaming, Wang, Yu, Ding, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374511/
https://www.ncbi.nlm.nih.gov/pubmed/25710274
http://dx.doi.org/10.7554/eLife.05118