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Detecting primitive hematopoietic stem cells in total nucleated and mononuclear cell fractions from umbilical cord blood segments and units

BACKGROUND: Rare hematopoietic stem cell populations are responsible for the transplantation engraftment process. Umbilical cord blood (UCB) is usually processed to the total nucleated cell (TNC), but not to the mononuclear cell (MNC) fraction. TNC counts are used to determine UCB unit storage, rele...

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Detalles Bibliográficos
Autores principales: Patterson, John, Moore, Cally H, Palser, Emily, Hearn, Jason C, Dumitru, Daniela, Harper, Holli A, Rich, Ivan N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374586/
https://www.ncbi.nlm.nih.gov/pubmed/25784613
http://dx.doi.org/10.1186/s12967-015-0434-z