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Detecting primitive hematopoietic stem cells in total nucleated and mononuclear cell fractions from umbilical cord blood segments and units
BACKGROUND: Rare hematopoietic stem cell populations are responsible for the transplantation engraftment process. Umbilical cord blood (UCB) is usually processed to the total nucleated cell (TNC), but not to the mononuclear cell (MNC) fraction. TNC counts are used to determine UCB unit storage, rele...
Autores principales: | Patterson, John, Moore, Cally H, Palser, Emily, Hearn, Jason C, Dumitru, Daniela, Harper, Holli A, Rich, Ivan N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374586/ https://www.ncbi.nlm.nih.gov/pubmed/25784613 http://dx.doi.org/10.1186/s12967-015-0434-z |
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