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Prognostic role of serum p53 antibodies in lung cancer

BACKGROUND: Mutations in the TP53 (Tumour Protein 53) gene can lead to expression of mutant p53 proteins that accumulate in cancer cells and can induce circulating p53 antibodies in cancer patients. Our aim was to evaluate the presence and prognostic role of these antibodies in lung cancer patients...

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Detalles Bibliográficos
Autores principales: Mattioni, Manlio, Soddu, Silvia, Prodosmo, Andrea, Visca, Paolo, Conti, Salvatore, Alessandrini, Gabriele, Facciolo, Francesco, Strigari, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374590/
https://www.ncbi.nlm.nih.gov/pubmed/25884692
http://dx.doi.org/10.1186/s12885-015-1174-4