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Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae

BACKGROUND: To achieve high-level production of non-native isoprenoid products, it requires the metabolic flux to be diverted from the production of sterols to the heterologous metabolic reactions. However, there are limited tools for restricting metabolic flux towards ergosterol synthesis. In the p...

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Detalles Bibliográficos
Autores principales: Yuan, Jifeng, Ching, Chi-Bun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374593/
https://www.ncbi.nlm.nih.gov/pubmed/25889168
http://dx.doi.org/10.1186/s12934-015-0220-x