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Dynamic control of ERG9 expression for improved amorpha-4,11-diene production in Saccharomyces cerevisiae
BACKGROUND: To achieve high-level production of non-native isoprenoid products, it requires the metabolic flux to be diverted from the production of sterols to the heterologous metabolic reactions. However, there are limited tools for restricting metabolic flux towards ergosterol synthesis. In the p...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374593/ https://www.ncbi.nlm.nih.gov/pubmed/25889168 http://dx.doi.org/10.1186/s12934-015-0220-x |