Depletion of PHD3 Protects Heart from Ischemia/Reperfusion Injury by Inhibiting Cardiomyocyte Apoptosis

PHD3, a member of a family of Prolyl-4 Hydroxylase Domain (PHD) proteins, has long been considered a pro-apoptotic protein. Although the pro-apoptotic effect of PHD3 requires its prolyl hydroxylase activity, it may be independent of HIF-1α, the common substrate of PHDs. PHD3 is highly expressed in t...

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Detalles Bibliográficos
Autores principales: Xie, Liang, Pi, Xinchun, Wang, Zhongjing, He, Jun, Willis, Monte S., Patterson, Cam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374643/
https://www.ncbi.nlm.nih.gov/pubmed/25633836
http://dx.doi.org/10.1016/j.yjmcc.2015.01.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374643/
https://www.ncbi.nlm.nih.gov/pubmed/25633836
http://dx.doi.org/10.1016/j.yjmcc.2015.01.007

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