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Functional Genomic Analysis Identifies Indoxyl Sulfate as a Major, Poorly Dialyzable Uremic Toxin in End-Stage Renal Disease

BACKGROUND: Chronic renal failure is characterized by progressive renal scarring and accelerated arteriosclerotic cardiovascular disease despite what is considered to be adequate hemodialysis or peritoneal dialysis. In rodents with reduced renal mass, renal scarring has been attributed to poorly fil...

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Detalles Bibliográficos
Autores principales: Jhawar, Sachin, Singh, Prabhjot, Torres, Daniel, Ramirez-Valle, Francisco, Kassem, Hania, Banerjee, Trina, Dolgalev, Igor, Heguy, Adriana, Zavadil, Jiri, Lowenstein, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374671/
https://www.ncbi.nlm.nih.gov/pubmed/25811877
http://dx.doi.org/10.1371/journal.pone.0118703