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Maternal Nicotine Exposure Leads to Impaired Disulfide Bond Formation and Augmented Endoplasmic Reticulum Stress in the Rat Placenta

Maternal nicotine exposure has been associated with many adverse fetal and placental outcomes. Although underlying mechanisms remain elusive, recent studies have identified that augmented endoplasmic reticulum (ER) stress is linked to placental insufficiency. Moreover, ER function depends on proper...

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Detalles Bibliográficos
Autores principales: Wong, Michael K., Nicholson, Catherine J., Holloway, Alison C., Hardy, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374683/
https://www.ncbi.nlm.nih.gov/pubmed/25811377
http://dx.doi.org/10.1371/journal.pone.0122295