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Herpesviral G Protein-Coupled Receptors Activate NFAT to Induce Tumor Formation via Inhibiting the SERCA Calcium ATPase

G protein-coupled receptors (GPCRs) constitute the largest family of proteins that transmit signal to regulate an array of fundamental biological processes. Viruses deploy diverse tactics to hijack and harness intracellular signaling events induced by GPCR. Herpesviruses encode multiple GPCR homolog...

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Detalles Bibliográficos
Autores principales: Zhang, Junjie, He, Shanping, Wang, Yi, Brulois, Kevin, Lan, Ke, Jung, Jae U., Feng, Pinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374719/
https://www.ncbi.nlm.nih.gov/pubmed/25811856
http://dx.doi.org/10.1371/journal.ppat.1004768