In Search of the Molecular Mechanisms Mediating the Inhibitory Effect of the GnRH Antagonist Degarelix on Human Prostate Cell Growth

Degarelix is a gonadrotropin-releasing hormone (GnRH) receptor (GnRHR) antagonist used in patients with prostate cancer who need androgen deprivation therapy. GnRHRs have been found in extra-pituitary tissues, including prostate, which may be affected by the GnRH and GnRH analogues used in therapy....

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Detalles Bibliográficos
Autores principales: Sakai, Monica, Martinez-Arguelles, Daniel B., Patterson, Nathan H., Chaurand, Pierre, Papadopoulos, Vassilios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374753/
https://www.ncbi.nlm.nih.gov/pubmed/25811175
http://dx.doi.org/10.1371/journal.pone.0120670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374753/
https://www.ncbi.nlm.nih.gov/pubmed/25811175
http://dx.doi.org/10.1371/journal.pone.0120670

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