Induction of Interferon-Stimulated Genes by IRF3 Promotes Replication of Toxoplasma gondii

Innate immunity is the first line of defense against microbial insult. The transcription factor, IRF3, is needed by mammalian cells to mount innate immune responses against many microbes, especially viruses. IRF3 remains inactive in the cytoplasm of uninfected cells; upon virus infection, it gets ph...

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Detalles Bibliográficos
Autores principales: Majumdar, Tanmay, Chattopadhyay, Saurabh, Ozhegov, Evgeny, Dhar, Jayeeta, Goswami, Ramansu, Sen, Ganes C., Barik, Sailen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374777/
https://www.ncbi.nlm.nih.gov/pubmed/25811886
http://dx.doi.org/10.1371/journal.ppat.1004779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374777/
https://www.ncbi.nlm.nih.gov/pubmed/25811886
http://dx.doi.org/10.1371/journal.ppat.1004779

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