Cargando…

Induction of Interferon-Stimulated Genes by IRF3 Promotes Replication of Toxoplasma gondii

Innate immunity is the first line of defense against microbial insult. The transcription factor, IRF3, is needed by mammalian cells to mount innate immune responses against many microbes, especially viruses. IRF3 remains inactive in the cytoplasm of uninfected cells; upon virus infection, it gets ph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Majumdar, Tanmay, Chattopadhyay, Saurabh, Ozhegov, Evgeny, Dhar, Jayeeta, Goswami, Ramansu, Sen, Ganes C., Barik, Sailen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374777/ https://www.ncbi.nlm.nih.gov/pubmed/25811886 http://dx.doi.org/10.1371/journal.ppat.1004779

Ejemplares similares

Unique nonstructural proteins of Pneumonia Virus of Mice (PVM) promote degradation of interferon (IFN) pathway components and IFN-stimulated gene proteins
por: Dhar, Jayeeta, et al.
Publicado: (2016)

RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway
por: Chattopadhyay, Saurabh, et al.
Publicado: (2016)

A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7
por: Subramanian, Gayatri, et al.
Publicado: (2018)

Inhibition of Viral Pathogenesis and Promotion of the Septic Shock Response to Bacterial Infection by IRF-3 Are Regulated by the Acetylation and Phosphorylation of Its Coactivators
por: Chattopadhyay, Saurabh, et al.
Publicado: (2013)

IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation
por: Popli, Sonam, et al.
Publicado: (2022)

Tryptophan-kynurenine pathway attenuates β-catenin-dependent pro-parasitic role of STING-TICAM2-IRF3-IDO1 signalosome in Toxoplasma gondii infection
por: Majumdar, Tanmay, et al.
Publicado: (2019)

FAF1 downregulation by Toxoplasma gondii enables host IRF3 mobilization and promotes parasite growth
por: Gao, Fei‐Fei, et al.
Publicado: (2021)

Non-replicating Toxoplasma gondii reverses tumor-associated immunosuppression
por: Fox, Barbara A, et al.
Publicado: (2013)

Toxoplasma gondii
por: Liesenfeld, Oliver
Publicado: (2009)

Effects of Interferon on Cells, Viruses and the Immune System
por: Sen, Ganes
Publicado: (1977)

Transfer Learning for Toxoplasma gondii Recognition
por: Li, Sen, et al.
Publicado: (2020)

Nontranscriptional Activity of Interferon Regulatory Factor 3 Protects Mice From High‐Fat Diet‐Induced Liver Injury
por: Sanz‐Garcia, Carlos, et al.
Publicado: (2019)

The transcriptome of Toxoplasma gondii
por: Radke, Jay R, et al.
Publicado: (2005)

Toxoplasma gondii and Schizophrenia
por: Torrey, E. Fuller, et al.
Publicado: (2003)

Toxoplasma gondii, Brazil
por: Gomez-Marin, Jorge
Publicado: (2007)

Prenatal Toxoplasma gondii
por: Linn, Edward S.
Publicado: (2011)

Organizational Changes of the Daughter Basal Complex during the Parasite Replication of Toxoplasma gondii
por: Hu, Ke
Publicado: (2008)

Internalization and TLR-dependent type I interferon production by Inflammatory monocytes to Toxoplasma gondii
por: Han, Seong-Ji, et al.
Publicado: (2014)

Toxoplasma gondii in Australian smallgoods
por: Momcilovic, Tatjana
Publicado: (2010)

Toxoplasma gondii in the Subarctic and Arctic
por: Prestrud, Kristin W, et al.
Publicado: (2010)

Drug Resistance in Toxoplasma gondii
por: Montazeri, Mahbobeh, et al.
Publicado: (2018)

Toxoplasma gondii in the Food Supply
por: Hussain, Malik A., et al.
Publicado: (2017)

Cell Death by Toxoplasma gondii
por: de Oliveira, Claudio Bruno Silva, et al.
Publicado: (2020)

Human immunity to Toxoplasma gondii
por: Fisch, Daniel, et al.
Publicado: (2019)

The pathogenicity and virulence of Toxoplasma gondii
por: Sanchez, Syrian G., et al.
Publicado: (2021)

The zebrafish as a novel model for the in vivo study of Toxoplasma gondii replication and interaction with macrophages
por: Yoshida, Nagisa, et al.
Publicado: (2020)

Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii
por: Watford, Wendy T., et al.
Publicado: (2008)

Interferon-Gamma Release Assay: An Effective Tool to Detect Early Toxoplasma gondii Infection in Mice
por: Yin, Qing, et al.
Publicado: (2015)

Toxoplasma gondii UBL-UBA Shuttle Protein DSK2s Are Important for Parasite Intracellular Replication
por: Zhang, Heng, et al.
Publicado: (2021)

Interferon Regulatory Factor (Irf)-1 and Irf-2 Regulate Interferon γ–Dependent Cyclooxygenase 2 Expression
por: Blanco, Jorge C. G., et al.
Publicado: (2000)

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii
por: Pawlowski, Nikolaus, et al.
Publicado: (2011)

Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection
por: Rinkenberger, Nicholas, et al.
Publicado: (2021)

HSPD1 Interacts with IRF3 to Facilitate Interferon-Beta Induction
por: Lin, Lan, et al.
Publicado: (2014)

Toxoplasma gondii infection in humans in China
por: Zhou, Peng, et al.
Publicado: (2011)

Laboratory diagnosis of Toxoplasma gondii infection
por: Calderaro, A., et al.
Publicado: (2009)

Toxoplasma gondii Prevalence, United States
por: Jones, Jeffrey L., et al.
Publicado: (2007)

Toxoplasma gondii and the blood-brain barrier
por: Feustel, Sabrina M., et al.
Publicado: (2012)

Unusual Presentation of Toxoplasma Gondii Encephalitis
por: Davis, Caleb, et al.
Publicado: (2012)

The Prevalence of Toxoplasma gondii in Hemodialysis Patients
por: Bayani, Masomeh, et al.
Publicado: (2013)

Toxoplasma gondii infection in immunocompromised individuals
por: Csep, Andrei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ikgir6kh544hct34g6ebmom2rs