Modulators of Hepatic Lipoprotein Metabolism Identified in a Search for Small-Molecule Inducers of Tribbles Pseudokinase 1 Expression

Recent genome wide association studies have linked tribbles pseudokinase 1 (TRIB1) to the risk of coronary artery disease (CAD). Based on the observations that increased expression of TRIB1 reduces secretion of VLDL and is associated with lower plasma levels of LDL cholesterol and triglycerides, hig...

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Detalles Bibliográficos
Autores principales: Nagiec, Marek M., Skepner, Adam P., Negri, Joseph, Eichhorn, Michelle, Kuperwasser, Nicolas, Comer, Eamon, Muncipinto, Giovanni, Subramanian, Aravind, Clish, Clary, Musunuru, Kiran, Duvall, Jeremy R., Foley, Michael, Perez, Jose R., Palmer, Michelle A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374785/
https://www.ncbi.nlm.nih.gov/pubmed/25811180
http://dx.doi.org/10.1371/journal.pone.0120295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374785/
https://www.ncbi.nlm.nih.gov/pubmed/25811180
http://dx.doi.org/10.1371/journal.pone.0120295

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