Cargando…

Impaired Oocyte Quality Induced by Dehydroepiandrosterone Is Partially Rescued by Metformin Treatment

The present study evaluated the influence of hyperandrogenism on oocyte quality using a murine PCOS model induced by dehydroepiandrosterone (DHEA) and further explored the effect of metformin treatment. Female BALB/c mice were treated with a vehicle control or DHEA (6 mg /100 g body weight) or DHEA...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Ying, Yu, Yang, Gao, Jiangman, Li, Rong, Zhang, Chunmei, Zhao, Hongcui, Zhao, Yue, Qiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374838/
https://www.ncbi.nlm.nih.gov/pubmed/25811995
http://dx.doi.org/10.1371/journal.pone.0122370