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Small RNA Sequencing for Profiling MicroRNAs in Long-Term Preserved Formalin-Fixed and Paraffin-Embedded Non-Small Cell Lung Cancer Tumor Specimens

BACKGROUND: The preservation of microRNAs in formalin-fixed and paraffin-embedded (FFPE) tissue makes them particularly useful for biomarker studies. The utility of small RNA sequencing for microRNA expression profiling of FFPE samples has yet to be determined. METHODS: Total RNA was extracted from...

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Detalles Bibliográficos
Autores principales: Buitrago, Daniel H., Patnaik, Santosh K., Kadota, Kyuichi, Kannisto, Eric, Jones, David R., Adusumilli, Prasad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374839/
https://www.ncbi.nlm.nih.gov/pubmed/25812157
http://dx.doi.org/10.1371/journal.pone.0121521