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YAP Enhances Autophagic Flux to Promote Breast Cancer Cell Survival in Response to Nutrient Deprivation

The Yes-associated protein (YAP), a transcriptional coactivator inactivated by the Hippo tumor suppressor pathway, functions as an oncoprotein in a variety of cancers. However, its contribution to breast cancer remains controversial. This study investigated the role of YAP in breast cancer cells und...

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Detalles Bibliográficos
Autores principales: Song, Qinghe, Mao, Beibei, Cheng, Jinbo, Gao, Yuhao, Jiang, Ke, Chen, Jun, Yuan, Zengqiang, Meng, Songshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374846/
https://www.ncbi.nlm.nih.gov/pubmed/25811979
http://dx.doi.org/10.1371/journal.pone.0120790