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Acquired Alterations of Hypothalamic Gene Expression of Insulin and Leptin Receptors and Glucose Transporters in Prenatally High-Glucose Exposed Three-Week Old Chickens Do Not Coincide with Aberrant Promoter DNA Methylation

BACKGROUND: Prenatal exposures may have a distinct impact for long-term health, one example being exposure to maternal ‘diabesity’ during pregnancy increasing offspring ‘diabesity’ risk. Malprogramming of the central nervous regulation of body weight, food intake and metabolism has been identified a...

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Detalles Bibliográficos
Autores principales: Rancourt, Rebecca C., Schellong, Karen, Ott, Raffael, Bogatyrev, Semen, Tzschentke, Barbara, Plagemann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374847/
https://www.ncbi.nlm.nih.gov/pubmed/25811618
http://dx.doi.org/10.1371/journal.pone.0119213