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The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH): Design of a pharmacogenetic Resource for Type 2 Diabetes

OBJECTIVE: Genome-wide association studies have uncovered a large number of genetic variants associated with type 2 diabetes or related phenotypes. In many cases the causal gene or polymorphism has not been identified, and its impact on response to anti-hyperglycemic medications is unknown. The Stud...

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Detalles Bibliográficos
Autores principales: Walford, Geoffrey A., Colomo, Natalia, Todd, Jennifer N., Billings, Liana K., Fernandez, Marlene, Chamarthi, Bindu, Warner, A. Sofia, Davis, Jaclyn, Littleton, Katherine R., Hernandez, Alicia M., Fanelli, Rebecca R., Lanier, Amelia, Barbato, Corinne, Ackerman, Rachel J., Khan, Sabina Q., Bui, Rosa, Garber, Laurel, Stolerman, Elliot S., Moore, Allan F., Huang, Chunmei, Kaur, Varinderpal, Harden, Maegan, Taylor, Andrew, Chen, Ling, Manning, Alisa K., Huang, Paul, Wexler, Deborah, McCarthy, Rita M., Lo, Janet, Thomas, Melissa K., Grant, Richard W., Goldfine, Allison, Hudson, Margo S., Florez, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374872/
https://www.ncbi.nlm.nih.gov/pubmed/25812009
http://dx.doi.org/10.1371/journal.pone.0121553