Antithrombin III Deficiency in Indian Patients with Deep Vein Thrombosis: Identification of First India Based AT Variants Including a Novel Point Mutation (T280A) that Leads to Aggregation

Antithrombin III (AT) is the main inhibitor of blood coagulation proteases like thrombin and factor Xa. In this study we report the identification and characterization of several variants of AT for the first time in Indian population. We screened 1950 deep vein thrombosis (DVT) patients for AT activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhakuni, Teena, Sharma, Amit, Rashid, Qudsia, Kapil, Charu, Saxena, Renu, Mahapatra, Manoranjan, Jairajpuri, Mohamad Aman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374914/
https://www.ncbi.nlm.nih.gov/pubmed/25811371
http://dx.doi.org/10.1371/journal.pone.0121889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374914/
https://www.ncbi.nlm.nih.gov/pubmed/25811371
http://dx.doi.org/10.1371/journal.pone.0121889

Ejemplares similares