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Testing for Mechanistic Interactions in Long-Term Follow-Up Studies

In follow-up studies, interactions are often assessed by including a cross-product term in a (multiplicative) Cox model. However, epidemiologists/clinicians often misinterpret a significant multiplicative interaction as a genuine mechanistic interaction. Though indices specific to mechanistic intera...

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Detalles Bibliográficos
Autores principales: Lin, Jui-Hsiang, Lee, Wen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374952/
https://www.ncbi.nlm.nih.gov/pubmed/25811982
http://dx.doi.org/10.1371/journal.pone.0121638