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Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control

Vaccines that trigger an influenza-specific cytotoxic T cell (CTL) response may aid pandemic control by limiting the transmission of novel influenza A viruses (IAV). We consider interventions with hypothetical CTL-inducing vaccines in a range of epidemiologically plausible pandemic scenarios. We est...

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Detalles Bibliográficos
Autores principales: Bolton, Kirsty J., McCaw, James M., Brown, Lorena, Jackson, David, Kedzierska, Katherine, McVernon, Jodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374977/
https://www.ncbi.nlm.nih.gov/pubmed/25811654
http://dx.doi.org/10.1371/journal.pone.0120138