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Chronopharmacokinetics of once daily dosed aminoglycosides in hospitalized infectious patients

Background hospitalized patients with serious infections treated with aminoglycosides are at risk of developing nephrotoxicity. Previous clinical studies have shown that the pharmacokinetics of aminoglycosides in humans follow a circadian rhythm. Therefore, the time of administration could have impo...

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Detalles Bibliográficos
Autores principales: van Maarseveen, Erik, Man, Wai Hong, Proost, Johannes, Neef, Cees, Touw, Daniël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375292/
https://www.ncbi.nlm.nih.gov/pubmed/25616626
http://dx.doi.org/10.1007/s11096-015-0066-7