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HCO(3)(−)-independent pH Regulation in Astrocytes in Situ Is Dominated by V-ATPase

The mechanisms of HCO(3)(−)-independent intracellular pH (pH(i)) regulation were examined in fibrous astrocytes within isolated neonatal rat optic nerve (RON) and in cultured cortical astrocytes. In agreement with previous studies, resting pH(i) in cultured astrocytes was 6.82 ± 0.06 and inhibition...

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Detalles Bibliográficos
Autores principales: Hansen, Daniel Bloch, Garrido-Comas, Nestor, Salter, Mike, Fern, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375461/
https://www.ncbi.nlm.nih.gov/pubmed/25666621
http://dx.doi.org/10.1074/jbc.M115.636597