Proteasomal Modulation of Cellular SNAT2 (SLC38A2) Abundance and Function by Unsaturated Fatty Acid Availability

Expression and activity of the System A/SNAT2 (SLC38A2) amino acid transporter is up-regulated by amino acid starvation and hypertonicity by a mechanism dependent on both ATF4-mediated transcription of the SLC38A2 gene and enhanced stabilization of SNAT2 itself, which forms part of an integrated cel...

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Detalles Bibliográficos
Autores principales: Nardi, Francesca, Hoffmann, Thorsten M., Stretton, Clare, Cwiklinski, Emma, Taylor, Peter M., Hundal, Harinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375474/
https://www.ncbi.nlm.nih.gov/pubmed/25653282
http://dx.doi.org/10.1074/jbc.M114.625137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375474/
https://www.ncbi.nlm.nih.gov/pubmed/25653282
http://dx.doi.org/10.1074/jbc.M114.625137

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