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Structural Insights into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2

Ets-2, like its closely related homologue Ets-1, is a member of the Ets family of DNA binding transcription factors. Both proteins are subject to multiple levels of regulation of their DNA binding and transactivation properties. One such regulatory mechanism is the presence of an autoinhibitory modu...

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Detalles Bibliográficos
Autores principales: Newman, Joseph A, Cooper, Christopher D. O., Aitkenhead, Hazel, Gileadi, Opher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375503/
https://www.ncbi.nlm.nih.gov/pubmed/25670864
http://dx.doi.org/10.1074/jbc.M114.619270