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GOAT – A simple LC-MS/MS gradient optimization tool

Modern nano-HPLC systems are capable of extremely precise control of solvent gradients, allowing high-resolution separation of peptides. Most proteomics laboratories use a simple linear analytical gradient for nano-LC-MS/MS experiments, though recent evidence indicates that optimized non-linear grad...

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Detalles Bibliográficos
Autores principales: Trudgian, David C, Fischer, Roman, Guo, Xiaofeng, Kessler, Benedikt M, Mirzaei, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375517/
https://www.ncbi.nlm.nih.gov/pubmed/24723505
http://dx.doi.org/10.1002/pmic.201300524