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Capsaicin Interaction with TRPV1 Channels in a Lipid Bilayer: Molecular Dynamics Simulation

Transient receptor potential vanilloid subtype 1 (TRPV1) is a heat-sensitive ion channel also involved in pain sensation, and is the receptor for capsaicin, the active ingredient of hot chili peppers. The recent structures of TRPV1 revealed putative ligand density within the S1 to S4 voltage-sensor-...

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Detalles Bibliográficos
Autores principales: Hanson, Sonya M., Newstead, Simon, Swartz, Kenton J., Sansom, Mark S.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375533/
https://www.ncbi.nlm.nih.gov/pubmed/25809255
http://dx.doi.org/10.1016/j.bpj.2015.02.013