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Regional differences in fiber tractography predict neurodevelopmental outcomes in neonates with infantile Krabbe disease

BACKGROUND: Krabbe disease is a fatal neurodegenerative disease caused by rapid demyelination of the central and peripheral nervous systems. The only available treatment, unrelated umbilical cord blood transplantation, is effective only if performed before clinical symptoms appear. Phenotypic expres...

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Detalles Bibliográficos
Autores principales: Gupta, A., Poe, M.D., Styner, M.A., Panigrahy, A., Escolar, M.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375637/
https://www.ncbi.nlm.nih.gov/pubmed/25844309
http://dx.doi.org/10.1016/j.nicl.2014.09.014