Cargando…

Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: Evidence from two independent cohorts

Polygenic risk scores, based on risk variants identified in genome-wide-association-studies (GWAS), explain a considerable portion of the heritability for schizophrenia (SZ) and bipolar disorder (BD). However, little is known about the combined effects of these variants, although polygenic neuroimag...

Descripción completa

Detalles Bibliográficos
Autores principales: Oertel-Knöchel, Viola, Lancaster, Thomas M., Knöchel, Christian, Stäblein, Michael, Storchak, Helena, Reinke, Britta, Jurcoane, Alina, Kniep, Jonathan, Prvulovic, David, Mantripragada, Kiran, Tansey, Katherine E., O’Donovan, Michael C., Owen, Michael J., Linden, David E.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375641/
https://www.ncbi.nlm.nih.gov/pubmed/25844328
http://dx.doi.org/10.1016/j.nicl.2015.03.005