A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3

Ataxin-3 is the protein responsible for the neurodegenerative polyglutamine disease Spinocerebellar ataxia type 3. Full structural characterisation of ataxin-3 is required to aid in understanding the mechanism of disease. Despite extensive study, little is known about the conformational properties o...

Descripción completa

Detalles Bibliográficos
Autores principales: Scarff, Charlotte A., Sicorello, Alessandro, Tomé, Ricardo J.L., Macedo-Ribeiro, Sandra, Ashcroft, Alison E., Radford, Sheena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375668/
https://www.ncbi.nlm.nih.gov/pubmed/25844046
http://dx.doi.org/10.1016/j.ijms.2012.08.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375668/
https://www.ncbi.nlm.nih.gov/pubmed/25844046
http://dx.doi.org/10.1016/j.ijms.2012.08.032

Ejemplares similares