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Transcript and protein expression decoupling reveals RNA binding proteins and miRNAs as potential modulators of human aging

BACKGROUND: In studies of development and aging, the expression of many genes has been shown to undergo drastic changes at mRNA and protein levels. The connection between mRNA and protein expression level changes, as well as the role of posttranscriptional regulation in controlling expression level...

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Detalles Bibliográficos
Autores principales: Wei, Yu-Ning, Hu, Hai-Yang, Xie, Gang-Cai, Fu, Ning, Ning, Zhi-Bin, Zeng, Rong, Khaitovich, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375924/
https://www.ncbi.nlm.nih.gov/pubmed/25853883
http://dx.doi.org/10.1186/s13059-015-0608-2