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Human iPSC-Derived Hepatocyte-like Cells Support Plasmodium Liver-Stage Infection In Vitro

Malaria eradication is a major goal in public health but is challenged by relapsing malaria species, expanding drug resistance, and the influence of host genetics on antimalarial drug efficacy. To overcome these hurdles, it is imperative to establish in vitro assays of liver-stage malaria for drug t...

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Detalles Bibliográficos
Autores principales: Ng, Shengyong, Schwartz, Robert E., March, Sandra, Galstian, Ani, Gural, Nil, Shan, Jing, Prabhu, Mythili, Mota, Maria M., Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375936/
https://www.ncbi.nlm.nih.gov/pubmed/25660406
http://dx.doi.org/10.1016/j.stemcr.2015.01.002