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In Vivo Repopulating Activity Emerges at the Onset of Hematopoietic Specification during Embryonic Stem Cell Differentiation

The generation of in vivo repopulating hematopoietic cells from in vitro differentiating embryonic stem cells has remained a long-standing challenge. To date, hematopoietic engraftment has mostly been achieved through the enforced expression of ectopic transcription factors. Here, we describe serum-...

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Detalles Bibliográficos
Autores principales: Pearson, Stella, Cuvertino, Sara, Fleury, Maud, Lacaud, Georges, Kouskoff, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375940/
https://www.ncbi.nlm.nih.gov/pubmed/25660408
http://dx.doi.org/10.1016/j.stemcr.2015.01.003