Structure of the hexameric HerA ATPase reveals a mechanism of translocation-coupled DNA-end processing in archaea

The HerA ATPase cooperates with the NurA nuclease and the Mre11-Rad50 complex for the repair of double-strand DNA breaks in thermophilic archaea. Here we extend our structural knowledge of this minimal end-resection apparatus by presenting the first crystal structure of hexameric HerA. The full-leng...

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Detalles Bibliográficos
Autores principales: Rzechorzek, Neil J., Blackwood, John K., Bray, Sian M., Maman, Joseph D., Pellegrini, Luca, Robinson, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376295/
https://www.ncbi.nlm.nih.gov/pubmed/25420454
http://dx.doi.org/10.1038/ncomms6506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376295/
https://www.ncbi.nlm.nih.gov/pubmed/25420454
http://dx.doi.org/10.1038/ncomms6506

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