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Structure of the hexameric HerA ATPase reveals a mechanism of translocation-coupled DNA-end processing in archaea
The HerA ATPase cooperates with the NurA nuclease and the Mre11-Rad50 complex for the repair of double-strand DNA breaks in thermophilic archaea. Here we extend our structural knowledge of this minimal end-resection apparatus by presenting the first crystal structure of hexameric HerA. The full-leng...
Autores principales: | Rzechorzek, Neil J., Blackwood, John K., Bray, Sian M., Maman, Joseph D., Pellegrini, Luca, Robinson, Nicholas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376295/ https://www.ncbi.nlm.nih.gov/pubmed/25420454 http://dx.doi.org/10.1038/ncomms6506 |
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