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Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury

Hepatocytes provide most liver functions, but they can also proliferate and regenerate the liver after injury. However, under some liver injury conditions, particularly chronic liver injury where hepatocyte proliferation is impaired, liver stem cells (LSCs) are thought to replenish lost hepatocytes....

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Detalles Bibliográficos
Autores principales: Schaub, Johanna R., Malato, Yann, Gormond, Coralie, Willenbring, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376310/
https://www.ncbi.nlm.nih.gov/pubmed/25131204
http://dx.doi.org/10.1016/j.celrep.2014.07.003