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Systematic computation with functional gene-sets among leukemic and hematopoietic stem cells reveals a favorable prognostic signature for acute myeloid leukemia

BACKGROUND: Genes that regulate stem cell function are suspected to exert adverse effects on prognosis in malignancy. However, diverse cancer stem cell signatures are difficult for physicians to interpret and apply clinically. To connect the transcriptome and stem cell biology, with potential clinic...

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Detalles Bibliográficos
Autores principales: Yang, Xinan Holly, Li, Meiyi, Wang, Bin, Zhu, Wanqi, Desgardin, Aurelie, Onel, Kenan, de Jong, Jill, Chen, Jianjun, Chen, Luonan, Cunningham, John M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376348/
https://www.ncbi.nlm.nih.gov/pubmed/25887548
http://dx.doi.org/10.1186/s12859-015-0510-7