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Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis
Both BRCA1 and Beclin 1 (BECN1) are tumor suppressor genes, which are in close proximity on the human chromosome 17q21 breast cancer tumor susceptibility locus and are often concurrently deleted. However, their importance in sporadic human breast cancer is not known. To interrogate the effects of BE...
Autores principales: | Tang, Hao, Sebti, Salwa, Titone, Rossella, Zhou, Yunyun, Isidoro, Ciro, Ross, Theodora S., Hibshoosh, Hanina, Xiao, Guanghua, Packer, Milton, Xie, Yang, Levine, Beth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376376/ https://www.ncbi.nlm.nih.gov/pubmed/25825707 http://dx.doi.org/10.1016/j.ebiom.2015.01.008 |
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