Decreased BECN1 mRNA Expression in Human Breast Cancer is Associated With Estrogen Receptor-Negative Subtypes and Poor Prognosis

Both BRCA1 and Beclin 1 (BECN1) are tumor suppressor genes, which are in close proximity on the human chromosome 17q21 breast cancer tumor susceptibility locus and are often concurrently deleted. However, their importance in sporadic human breast cancer is not known. To interrogate the effects of BE...

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Detalles Bibliográficos
Autores principales: Tang, Hao, Sebti, Salwa, Titone, Rossella, Zhou, Yunyun, Isidoro, Ciro, Ross, Theodora S., Hibshoosh, Hanina, Xiao, Guanghua, Packer, Milton, Xie, Yang, Levine, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376376/
https://www.ncbi.nlm.nih.gov/pubmed/25825707
http://dx.doi.org/10.1016/j.ebiom.2015.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376376/
https://www.ncbi.nlm.nih.gov/pubmed/25825707
http://dx.doi.org/10.1016/j.ebiom.2015.01.008

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