Isolation, Characterization, and Autophagy Function of BECN1-Splicing Isoforms in Cancer Cells

Alternative splicing allows the synthesis of different protein variants starting from a single gene. Human Beclin 1 (BECN1) is a key autophagy regulator that acts as haploinsufficient tumor suppressor since its decreased expression correlates with tumorigenesis and poor prognosis in cancer patients....

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Detalles Bibliográficos
Autores principales: Maheshwari, Chinmay, Vidoni, Chiara, Titone, Rossella, Castiglioni, Andrea, Lora, Claudia, Follo, Carlo, Isidoro, Ciro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405542/
https://www.ncbi.nlm.nih.gov/pubmed/36008963
http://dx.doi.org/10.3390/biom12081069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405542/
https://www.ncbi.nlm.nih.gov/pubmed/36008963
http://dx.doi.org/10.3390/biom12081069

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