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Co-Encapsulating the Fusogenic Peptide INF7 and Molecular Imaging Probes in Liposomes Increases Intracellular Signal and Probe Retention

Liposomes are promising vehicles to deliver diagnostic and therapeutic agents to cells in vivo. After uptake into cells by endocytosis, liposomes are degraded in the endolysosomal system. Consequently, the encapsulated cargo molecules frequently remain sequestered in endosomal compartments; this lim...

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Detalles Bibliográficos
Autores principales: Burks, Scott R., Legenzov, Eric A., Martin, Erik W., Li, Changqing, Lu, Wuyuan, Kao, Joseph P. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376389/
https://www.ncbi.nlm.nih.gov/pubmed/25816348
http://dx.doi.org/10.1371/journal.pone.0120982