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Co-Encapsulating the Fusogenic Peptide INF7 and Molecular Imaging Probes in Liposomes Increases Intracellular Signal and Probe Retention
Liposomes are promising vehicles to deliver diagnostic and therapeutic agents to cells in vivo. After uptake into cells by endocytosis, liposomes are degraded in the endolysosomal system. Consequently, the encapsulated cargo molecules frequently remain sequestered in endosomal compartments; this lim...
Autores principales: | Burks, Scott R., Legenzov, Eric A., Martin, Erik W., Li, Changqing, Lu, Wuyuan, Kao, Joseph P. Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376389/ https://www.ncbi.nlm.nih.gov/pubmed/25816348 http://dx.doi.org/10.1371/journal.pone.0120982 |
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