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Sal-like protein 2 upregulates p16 expression through a proximal promoter element

Sal-like protein 2 (Sall2), a homeotic transcription factor, is a putative tumor suppressor. We have previously shown that Sall2 activates the transcription of tumor suppressor gene p21 and suppresses tumorigenesis through cell cycle inhibition and induction of apoptosis. To investigate additional S...

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Detalles Bibliográficos
Autores principales: Wu, Zhenghua, Cheng, Kebin, Shi, Lidan, Li, Zheqi, Negi, Hema, Gao, Guangwei, Kamle, Suchitra, Li, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376433/
https://www.ncbi.nlm.nih.gov/pubmed/25580951
http://dx.doi.org/10.1111/cas.12606