UVA photoactivation of DNA containing halogenated thiopyrimidines induces cytotoxic DNA lesions

Photochemotherapy, the combination of a photosensitiser and ultraviolet (UV) or visible light, is an effective treatment for skin conditions including cancer. The high mutagenicity and non-selectivity of photochemotherapy regimes warrants the development of alternative approaches. We demonstrate tha...

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Detalles Bibliográficos
Autores principales: Brem, Reto, Zhang, Xiaohui, Xu, Yao-Zhong, Karran, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Sequoia 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376468/
https://www.ncbi.nlm.nih.gov/pubmed/25747491
http://dx.doi.org/10.1016/j.jphotobiol.2015.02.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376468/
https://www.ncbi.nlm.nih.gov/pubmed/25747491
http://dx.doi.org/10.1016/j.jphotobiol.2015.02.012

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